PhD Candidate in Medicinal Chemistry | University at Buffalo
I am a PhD candidate in Medicinal Chemistry at the University at Buffalo. My research focuses on enzyme mechanism and inhibitor design, including studies on DXR and HDAC11 to develop selective chemical probes.
My currwent research focuses on understanding the mechanism of 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR), which catalyzes the first committed step in the non-mevalonate (MEP) pathway responsible for isoprenoid biosynthesis. Through kinetic isotope effect (KIE) studies, we aim to establish the transition state model of DXR computationally, which can serve as a blueprint for the future design of tight-binding inhibitors of this drug target.
Research/Teaching Assistant, Department of Chemistry, University at Buffalo
President, Nigerian Graduate Students Association (NGSA)
Judge, Ohio Academy of Science State Science Day
Email: oeadewal@buffalo.edu
Download my CV